Infusion Automation

Expert infusion automation for your high sensitivity metabolomics and lipidomics experiments

High-throughput, high sensitivity and low carryover: the new infusion automation from Trajan LEAP Automation offers you everything you need to bring your lipidomics mass spec workflow to its peak performance.

Move from manual sample infusion to the highest standard of infusion automation. With rapid cleanup between injections and best-in-class software architecture to integrate into your workflow, our infusion automation will elevate your lipidomics experiments.

"We just ran a whole pile of samples. It ran 24/7 without a hitch. Very reliable."

- Calvin Vary, PhD

Proteomics and Lipidomics Core Facility, Maine Medical Center Research Institute 

The most consistent and flexible system available - eliminating carryover while saving you time

  • Sample infusion at flow rates between 5 and 100uL/min -- directly into your ESI source -- precisely and without pulsation
  • Compatible with both shotgun and targeted lipid analysis
  • Exclusive inert configuration is available for your trickiest lipid classes -- ensuring your samples never come into contact with any polymers

The illustration below shows how this rapid washing is achieved. After washing the inside, the system will wash the needle externally and be ready to aspirate the next sample.

Infusion diagram

Greatest experimental control with powerful, user-friendly software

  • Built on our Chronos software = maximum compatibility with your preferred CDS, LIMS and MS data systems
  • MS acquisition mode switching within a single infusion
  • Method parameters are available for flow rates, infusion times, stabilization delays and cleanup conditions
  • With an optional second valve, standard chromatography methods can be used in the same sequence with direct infusion samples

Example Chronos method for infusion sample:

Chronos infusion method


Flow rate range 5—100μL/min
Sample formats Sealed and unsealed vials (1mL, 2mL, 10mL); sealed and unsealed plates (96 and 384-well)
Optional features Sample cooling drawers (4-40°C), inert flow path, 2nd valve for chromatography autosampling
Sample capacity Expandable capacity, from three plate tray holder, to 6 or 12 plate drawer stack(s). Capacity depends on vial/tray formats and drawer configuration, maximum 4 stacks
Signal stability Signal stability on a single sample has been demonstrated for 20 minutes. Long term stability confirmed in successful analysis of 400 samples over a 36-hour period (5 minute injection per sample).